# Drug combination for treatment resistant depression no more effective than single

**URL:** https://archive.menshealtharchive.com/t/drug-combination-for-treatment-resistant-depression-no-more-effective-than-single/871
**Category:** Research Database
**Created:** [November 4, 2018, 1:45am UTC](https://archive.menshealtharchive.com/t/drug-combination-for-treatment-resistant-depression-no-more-effective-than-single/871 "2018-11-04T01:45:03Z")
**Posts on this page:** 1
**Page:** 1

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### Author: ![menshealtharchive](https://yyz1.discourse-cdn.com/flex035/user_avatar/archive.menshealtharchive.com/menshealtharchive/32/587_2.png) [@menshealtharchive](https://archive.menshealtharchive.com/u/menshealtharchive)
#### Post date: [November 4, 2018, 1:45am UTC](https://archive.menshealtharchive.com/t/drug-combination-for-treatment-resistant-depression-no-more-effective-than-single/871/1 "2018-11-04T01:45:03Z")

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> **[Drug combination for treatment resistant depression no more effective than...](https://www.sciencedaily.com/releases/2018/11/181101133833.htm)**
>
> A large clinical trial, looked at the effectiveness of adding mirtazapine to an SSRI or SNRI in patients who remain depressed after at least six weeks of conventional (SSRI or SNRI) antidepressant treatment. They found that this combination was no...

  
A large clinical trial, looked at the effectiveness of adding mirtazapine to an SSRI or SNRI in patients who remain depressed after at least six weeks of conventional (SSRI or SNRI) antidepressant treatment. They found that this combination was no more effective in improving depression than placebo and call on doctors to rethink its use.