# Decades-old question about protein found in Alzheimer's brain plaques

**URL:** <https://archive.menshealtharchive.com/t/decades-old-question-about-protein-found-in-alzheimers-brain-plaques/1562>\
**Category:** Research Database\
**Created:** [January 10, 2019, 10:49pm UTC](https://archive.menshealtharchive.com/t/decades-old-question-about-protein-found-in-alzheimers-brain-plaques/1562 "2019-01-10T22:49:15Z")\
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**Author:** ![menshealtharchive](https://yyz1.discourse-cdn.com/flex035/user_avatar/archive.menshealtharchive.com/menshealtharchive/32/587_2.png) [@menshealtharchive](https://archive.menshealtharchive.com/u/menshealtharchive)\
**Post date:** [January 10, 2019, 10:49pm UTC](https://archive.menshealtharchive.com/t/decades-old-question-about-protein-found-in-alzheimers-brain-plaques/1562/1 "2019-01-10T22:49:15Z")

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> **[Decades-old question about protein found in Alzheimer's brain plaques](https://www.sciencedaily.com/releases/2019/01/190110141755.htm)**
>
> Alzheimer's-affected brains are riddled with so-called amyloid plaques: protein aggregates consisting mainly of amyloid-beta. However, this amyloid-beta is a fragment produced from a precursor protein whose normal function has remained enigmatic for...

  
Alzheimer’s-affected brains are riddled with so-called amyloid plaques: protein aggregates consisting mainly of amyloid-beta. However, this amyloid-beta is a fragment produced from a precursor protein whose normal function has remained enigmatic for decades. A team of scientists has now uncovered that this amyloid precursor protein modulates neuronal signal transmission through binding to a specific receptor. Modulating this receptor could potentially help treat Alzheimer’s or other brain diseases.